Reno: regularized non-parametric analysis of protein lysate array data
نویسندگان
چکیده
منابع مشابه
Reno: regularized non-parametric analysis of protein lysate array data
MOTIVATION The reverse-phase protein lysate arrays have been used to quantify the relative expression levels of a protein in a number of cellular samples simultaneously. To avoid quantification bias due to mis-specification of commonly used parametric models, a nonparametric approach based on monotone response curves may be used. The existing methods, however, aggregate the protein concentratio...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2012
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bts131